Label-free and Multi-parametric Monitoring of Cell-based Assays with Substrate-embedded Sensors Rutilius Taurus Aemilianus 4Selbstzahler12

4Selbstzahler12

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Label-free and Multi-parametric Monitoring of Cell-based Assays with Substrate-embedded Sensors Rutilius Taurus Aemilianus 4Selbstzahler12This thesis describes novel substrate embedded physical sensors that can be used to monitor different types of cell based assays non invasively and label free. The sensors described provide integrative information of the cells under study with an adaptable time resolution (ranging from milliseconds to days). This information about the dynamic cell response to chemical, physical or biological stimuli defines a new paradigm in fundamental biomedical