Gene Vaccines formatIsbn:Softcover - 9783709119297 and Savannah River site

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Gene Vaccines formatIsbn:Softcover - 9783709119297 and Savannah River siteThe induction of antigen specific immune responses after in vivo transfection with expression plasmids has triggered a revolution of vaccine research. After a first hype, evoked by the fascinating options of this method, clinical studies did not reach the ambitious aims and a phase of disillusion ensued. It became obvious that Gene vaccines displayed a weaker immunogenicity in humans than had been observed in the mouse models. Meanwhile these hurdles